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Description

Cycle length should not be guessed or extended without medical guidance

Vagal afferent neurons (VANs) expressing GLP-1Rs innervate intestinal mucosa and hepatic portal vasculature, suggesting these pathways may transduce peripheral GLP-1 RA effects to central satiety and glucoregulatory centers 57,58,59

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Initial treatment may involve daily injections, followed by weekly or monthly maintenance schedule as determined by healthcare provider based on patient response